He was born 24 Aug 1668 in Monterrey. His father was Joseph Martinez Guajardo, and his mother was Nicolasa de la Garza de la Rocha.
He married Margarita Gertrudis Gutierrez de Castro, daughter of Diego Gutierrez de Castro and Gertrudis de la Garza on 20 Sep 1693 in Monterrey. He was 25 years old, and the bride was 18 years old.
Isabel Juana Guajardo. She married Joaquin Garcia.
Joaquin Guajardo. He married Lucia Rodriguez. He owned Camargo 27 (tract), Camargo 46 (tract).
Maria Gertrudis Guajardo, born 1695. She married Francisco Garcia, son of Juan Garcia and Lucia de Salinas.
Ana Maria Guajardo, baptized 7 Jul 1702 in Monterrey. She married Jose Jacinto de la Peña in Cerralvo?. She owned Mier 48 (tract).
Antonia Margarita Guajardo, baptized 21 Jan 1708. She married Francisco Javier Chapa, son of Jose Maria Chapa and Josefa Sanchez de la Barrera on 4 Feb 1727.
Josefa Guajardo, born 1720. She married Francisco de la Garza Falcon, son of Francisco Narciso de la Garza Falcon and Maria Chapa. She owned Camargo 73 (tract).
Maria de Jesus Guajardo, born 1727. She married Jose Valentin Olivares, son of Juan de Olivares Benavides and Maria Vela de los Reyes.
Will in Monterrey Protocols, 1728, p.15