Diego Gutierrez de Castro was the son of Diego Gutierrez de Castro and Juana Francisca Ayala de Ovalle.
He married Gertrudis Flores de la Garza on 30 Jul 1673 in Monterrey.
Ignacio Gutierrez married Josefa de Arellano.
Margarita Gertrudis Gutierrez de Castro was baptized on 23 Jun 1675 in Monterrey. She married Joseph Martinez Guajardo.