He was born circa 1646. His father was Lorenzo Martinez Guajardo, and his mother was Yldefonsa Flores de Valdez.
In 1667, he requested a dispensation to marry Nicolasa de la Garza de la Rocha. He was 21 years old, and the bride was 19 years old. Dispensation source: Guerra, et. al., Index to the Marriage Investigations of the Diocese of Guadalajara, p.164.
Geronima Guajardo. She married Juan de Treviño.
Rosa Guajardo. In 1702, she requested a dispensation to marry Antonio Feliciano de la Garza Sosa.
Joseph Martinez Guajardo, born 1668 in Monterrey. He married Margarita Gertrudis Gutierrez de Castro, daughter of Diego Gutierrez de Castro and Gertrudis de la Garza on 20 Sep 1693 in Monterrey.