She was born circa 1752. Her father was Lazaro Vela, and her mother was Maria Antonia Garcia. Her father owned Porción 57, Mier. In 1782, she lived in Las Animas in household number 96. The church census recorded that she was married, española, and 30 years old. Her household included 9 people.
She married Juan Pantaleon Izaguirre, son of Martin Izaguirre and Juana Hernandez. It was his second marriage. He owned Porción 55, Mier, Starr County, Porción 56, Mier. Her husband died on 15 Nov 1802. He was 80 years old.
Maria Antonia de la Encarnacion Izaguirre Vela, baptized 2 Apr 1767 in Mier. She married Jose Miguel Ramirez, son of Jose Cristobal Ramirez and Maria Matiana Hinojosa on 3 Jan 1783 in Mier. Their padrino was Juan Antonio Canales, and their madrina was Maria de los Santos Garcia.
Maria Norberta Izaguirre Vela, baptized 17 Jun 1769. She married Jose Salvador Ramos, son of Pedro Eufracio Ramos and Maria Teodora Canales on 1 Dec 1801. Her husband died on 9 Sep 1813 in the vicinity of the Rio Grande - probably near Las Animas or Los Arrieros. Cause of death: killed by Indians.
Jose Manuel Izaguirre Vela, born 1771. He married Maria Dorotea Gonzalez, daughter of Jose Marcelino Gonzalez and Maria Gertrudis Ramos on 3 Mar 1791.
Maria Luisa Izaguirre Vela, born 1774. She married Jose Ventura Gonzalez, son of Alvino Gonzalez and Ana Lucia Salinas on 1 Feb 1798. Her husband died on 9 Sep 1813 in the vicinity of the Rio Grande - probably near Las Animas. Cause of death: killed by Indians. He was 42 years old.
Maria Manuela Izaguirre Vela, born 1777. She married Francisco Javier Gonzalez, son of Juan Jose Gonzalez and Maria Clara Salinas. Her husband died on 9 Sep 1813 in the vicinity of the Rio Grande - probably near Las Animas. Cause of death: killed by Indians. He was 45 years old.
Jose Rafael Izaguirre Vela, born 1779. He married Refugio Ramirez, daughter of Jose Luis Ramirez Hinojosa and Basilia Martinez.