He was born circa 1743. His father was Bartolome de Cuellar, and his mother was Gregoria Martinez.
He married Maria Tomasa Gutierrez de Lara, daughter of Bernabe Gutierrez de Lara and Antonia de la Garza Falcon. Her father owned Revilla 14 grant, Zapata County.
He married Gertrudis Ramirez, daughter of Jose Cristobal Ramirez and Maria Matiana Hinojosa. It was his second marriage. Her father owned Revilla 17 grant, Zapata County.
Maria del Refugio Cuellar. She married Jose Eugenio Ramirez Hinojosa, son of Jose Cristobal Ramirez and Maria Matiana Hinojosa.