He was born circa 1743. His father was Bartolome de Cuellar, and his mother was Gregoria Martinez.
He married Maria Tomasa Gutierrez de Lara, daughter of Bernabe Gutierrez de Lara and Antonia de la Garza Falcon. Her father owned Porción 14, Revilla, Zapata County.
He married Gertrudis Ramirez, daughter of Jose Cristobal Ramirez and Maria Matiana Hinojosa. It was his second marriage. Her father owned Porción 17, Revilla, Zapata County.