He married Alfonsa (Ildefonsa) Martinez Guajardo in Jun 1698.

He married Francisca Javiera Flores on 9 Sep 1704 in Monclova.

Nicolas Ecay Muzquiz.

Manuela Ignacia Ecay Muzquiz married Lorenzo de Hoyos Solar y Piedra.

Joseph Miguel Ecay Muzquiz was baptized on 3 Jun 1698 in Monclova.

Juana Javiera Ecay Muzquiz was born circa 1706. She married Bartolome Torralba.

Joseph Joaquin Ecay Muzquiz was baptized on 6 Apr 1707 in Monclova. He married Mariana de la Garza Falcon.

Maria Rosa Ecay Muzquiz was baptized on 18 Sep 1708 in Monclova.

Isabel Maria Ecay Muzquiz was baptized on 16 Mar 1710 in Monclova. She married Juan Francisco Ruiz de Santayana.

Antonia Javiera Ecay Muzquiz was baptized on 17 Sep 1711 in Monclova.

Maria Gertrudis Ecay Muzquiz was baptized on 16 Sep 1713 in Monclova.

Maria Josefa Ecay Muzquiz was baptized on 30 Sep 1715 in Monclova.

Melchora Marselina Ecay Muzquiz was baptized on 25 Apr 1717 in Monclova. She married Gaspar de Lombraña.

Francisco Joaquin Ecay Muzquiz was baptized on 28 Oct 1719 in Monclova.

Pedro Joseph Ecay Muzquiz was baptized on 11 Oct 1722 in Monclova.

Ana Maria Ecay Muzquiz was baptized on 27 Mar 1726 in Monclova.