Nicolas Martinez Guajardo was the son of Lorenzo Martinez Guajardo and Yldefonsa Flores de Valdez .
He married Micaela Guerra.
He married Isabel Mendez Tovar.
Juan Antonio Guajardo married Lucia de Cuellar.
Alfonsa (Ildefonsa) Martinez Guajardo was born circa 1670. She married Joseph Antonio Ecay Muzquiz.