He married Maria Ygnes de Peña on 22 Feb 1751 in Monterrey.

Jose Antonio Saldaña was baptized on 3 Feb 1752 in Monterrey. He married Maria Cayetana Lozano, Juana Maria Hernandez.

Juan Jose Sixto Saldaña was baptized on 20 Feb 1754 in Monterrey, a resident of San Pedro. He married Juana Francisca Guerra Ayala.

Pedro Jose Gil Saldaña was baptized on 15 Sep 1756 in Monterrey. He married Maria Guadalupe de Ayala, Maria Josefa Guajardo.

Maria Jusepa Vitorina Saldaña was baptized on 5 Jan 1761 in Monterrey.

Maria Teresa Saldaña was born circa 1762. She married Jose Mariano de las Casas Lobo Guerrero.

Maria Gertrudis Saldaña was baptized on 20 Oct 1764 in Monterrey.

Maria Francisca Saldaña was baptized on 14 Apr 1767 in Monterrey. She married Alexandro Verastegui, Jose Antonio Perez de Arispe.

Maria Manuela Saldaña was baptized on 26 Jan 1772 in Monterrey. She married Jose Antonio de Arispe.

Juan Jose Saldaña was baptized on 20 Feb 1775 in Monterrey. He married Maria Agustina Gonzalez, Maria de Carmen Verastegui.

Jose Gregorio Saldaña was baptized on 22 Mar 1778 in Monterrey. He married Maria Teresa Leal.