She was born 26 Mar 1792. Her father was Ramon Guajardo, and her mother was Josefa Ayala.
She married Pedro Saldaña, son of Francisco Saldaña and Maria Ygnes de Peña on 5 May 1808 in Monterrey. She was 16 years old, and the groom was 52 years old. It was his second marriage. Her husband died on 7 Nov 1809 in Monterrey. He was 53 years old.