He was born circa 1769. His father was Santiago Barrera, and his mother was Maria Salome Garcia. His father owned Porción 2, Mier. In 1782, he lived in Mier in household number 1. The church census recorded that he was a youth, español, and 13 years old. His household included 10 people. In 1791, he lived in Mier in household number 3. The church census recorded that he was single, español, and 22 years old. His household included 9 people.
He married Maria Matiana Moreno, daughter of Joaquin Moreno and Maria Barbara Vela.
Jose Maria Barrera. He married Concepcion Peña, daughter of Jose Bernardo Peña and Maria Balvina Garcia. He owned Randado grant, Jim Hogg County.
Santos Barrera. He married Paula Garza. He owned Las Cuevitas grant, Jim Hogg County, Texas.
Faustina Barrera, born 1794. She married Victoriano Gonzalez, son of Santiago Gonzalez and Maria Gertrudis Barrera. She married Jose Maria Guerra.
Juana Manuela Barrera, born 1796. She married Antonio Garcia, son of Tomas Garcia and Maria Josefa de la Garza.