Her father was Tomas Guajardo, and her mother was Maria Ignacia Villarreal.
She married Juan Jose Cisneros (Jimenez de Cisneros), son of Bartolome Cisneros and Maria Mariana Villegas. He owned land in Porción 79, Camargo.
Jose Antonio Cisneros. On 3 Feb 1781, he requested a dispensation to marry Ana Maria Perez, daughter of Miguel Perez and Bernarda Hinojosa in Camargo. He died on 31 Oct 1831 in Matamoros.
As the widow of the original grantee, she inherited Camargo 79 from Juan Jose Cisneros (Jimenez de Cisneros).
In 1790, she sold Camargo 79 to Manuel Tadeo Chavez de Caballero. The tract was sold in 1784 via extrajudicial deed and formalized in 1790. Sáenz Ramírez, Protocolos de Camargo p. 178; Seabury and Escobar, Family Tree Book, p. 352.