Her father was Rodrigo Flores de Valdez Carballo, and her mother was Maria Isabel de Salazar y Treviño.
She married Joseph de la Fuente, son of Domingo de la Fuente and Francisca Martinez Guajardo Rodriguez.
She married Lucas de Farias, son of Juan de Farias and Isabel Rodriguez. It was her second marriage.
Joseph de Farias. He married Ynes de Aguirre, daughter of Capt. Pedro de Aguirre and Antonia Guillen.
Isabel Flores de la Fuente (del Valle). She married Jacinto Garcia, son of Lorenzo Garcia and Juana de la Garza.
Ana de la Fuente. She married Sebastian Flores de Abrego, son of Diego Flores de Abrego.
Pedro Flores de la Fuente. He married Isabel Flores Camacho, daughter of Sebastian Flores de Abrego and Maria Camacho. He married Maria Galindo, daughter of Juan Galindo and Melchora Navarro.
Domingo de la Fuente. He married Teresa Cabello, daughter of Manuel Cabello and Maria de Farias.
Luisa de la Fuente. She married Diego de Morales.