His father was Rodrigo Flores de Valdez Carballo, and his mother was Maria Isabel de Salazar y Treviño.
He married Melchora Ramos de Arriola, daughter of Juan Ramos de Arriola and Maria Melendez.
He married _Guajardo?. It was his second marriage.
Ines Flores de Valdez. She married Diego Luis Sanchez, son of Martin Sanchez Suarez de Longoria and Antonia Rodriguez.
Alonso Flores de Valdez. He married Margarita de Aguirre, daughter of Capt. Pedro de Aguirre and Antonia Guillen.
Juana Flores de Valdez. She married Nicolas de Vega, son of Marcos de Vega. In 1693, she requested a dispensation to marry Francisco Gomez Mascorro.
Melchora Flores de Valdez. She married Nicolas de la Fuente, son of Domingo de la Fuente and Francisca Martinez Guajardo Rodriguez.
Alvaro Flores de Valdez. He married Maria Ximenez.
Josefa de Alvaro. She married _ Saucedo.