His father was Lazaro de la Garza Falcon, and his mother was Maria Inez Ayala Saldivar Sosa.
In 1701, he requested a dispensation to marry Maria Cavazos (Fernandez de Castro). Dispensation source: Guerra, et. al., Index to the Marriage Investigations of the Diocese of Guadalajara, p.274.
He married Teresa Caballero de los Olivos, daughter of Sgt. Maj. Lucas Caballero de los Olivos and Margarita Rodriguez de Montemayor. It was his second marriage, and her second marriage.
Maria Josefa de la Garza. In 1734, she requested a dispensation to marry Lorenzo Davila, son of Lorenzo Davila and Bernarda Flores Guajardo. In 1751, she requested a dispensation to marry Santiago Valdez, son of Francsico Flores de Valdez and Juana Sanchez Navarro.
Joseph de la Garza. In 1725, he requested a dispensation to marry Maria Gertrudis Mireles, daughter of Juan de Castro Mireles and Maria Teresa Caballero.
Maria Ignacia Cavazos. In 1748, she requested a dispensation to marry Francisco Javier de la Garza, son of Sebastian de la Garza and Clara Guerra.
Leonarda de la Garza. In 1732, she requested a dispensation to marry Juan Flores.