Manuel de la Garza was the son of Lazaro de la Garza Falcon and Maria Inez Ayala Saldivar Sosa.
He requested a dispensation to marry Maria Cavazos (Fernandez de Castro) in 1701. Dispensation source: Guerra et al., Index to the Marriage Investigations of the Diocese of Guadalajara, p.274.
He married Teresa Caballero de los Olivos.
Leonarda de la Garza married Juan Flores.