His father was Lazaro de la Garza Falcon, and his mother was Maria Inez Ayala Saldivar Sosa.
In 1701, he requested a dispensation to marry Maria Cavazos (Fernandez de Castro). Dispensation source: Guerra, et. al., Index to the Marriage Investigations of the Diocese of Guadalajara, p.274.
He married Teresa Caballero de los Olivos, daughter of Sgt. Maj. Lucas Caballero de los Olivos and Margarita Rodriguez de Montemayor. It was his second marriage, and her second marriage.
Maria Josefa de la Garza. In 1734, she requested a dispensation to marry Lorenzo Davila. In 1751, she requested a dispensation to marry Santiago Valdez.
Joseph de la Garza. In 1725, he requested a dispensation to marry Maria Gertrudis Mireles.
Maria Ignacia Cavazos. In 1748, she requested a dispensation to marry Francisco Javier de la Garza.
Leonarda de la Garza. In 1732, she requested a dispensation to marry Juan Flores.