Jose Rafael Ramirez was the son of Jose Miguel Ramirez Hinojosa and Maria Antonia Izaguirre.
He married Sinforiana Ramirez.
In 1852, as the son-in-law of the original grantee, he applied for confirmation of San Pedro del Charco Redondo from the State of Texas. He had occupied the land since death of Simon Ramirez, his father-in law.
In 1852 he applied for confirmation of Santa Rosalia from the State of Texas. He had occupied the land since death of Simon Ramirez, his father-in law. He applied for this tract as the same time as San Pedro del Charco Redondo.