His father was Geronimo Cantu, and his mother was Juliana de Treviño.
He married Antonia Ortiz.
He married Gertrudis de la Garza, daughter of Lazaro de la Garza Falcon and Petronila de Montemayor. It was his second marriage.
He married Maria de Villarreal, daughter of Francisco de Villarreal and Ursula de Izaguirre. It was his third marriage.
He married Antonia Ramirez in 1684. the bride was 16 years old. It was his fourth marriage.
Fernando Cantu. He married Antonia de Villarreal, daughter of Francisco de Villarreal and Ursula de Izaguirre.
Joseph Cantu. He married Gertrudis de la Garza, daughter of Joseph de la Garza and Nicolasa de la Garza.
Maria Cantu. In 1728, she requested a dispensation to marry Cristobal de Villarreal, son of Francisco de Villarreal and Ursula de Izaguirre.
Clara Cantu. She married Blas Garcia. In 1728, she requested a dispensation to marry Miguel de Villarreal, son of Cristobal de Villarreal and Micaela de Treviño.
Blas Cantu, born in Valle de Salinas. In 1730, he requested a dispensation to marry Ana Maria de la Garza, daughter of Bernabe de la Garza and Ana de Quintanilla. In 1751, he requested a dispensation to marry Maria Ignacia de Treviño, daughter of Joseph de Treviño and Maria Josefa Leal de Leon.
Maria Josefa Cantu. She married Antonio de Villarreal.
Antonio Cantu. He married Josefa de la Garza.
Maria Cantu. In 1686, she requested a dispensation to marry Juan Perez de la Garza, son of Pedro de la Garza Rodriguez and Maria Lucia Robles y de la Rocha.
Santiago Cantu. He married Maria Rosa de Arellano, daughter of Nicolas de Arellano and Lucia de la Garza.
Juan Cantu. He married Maria Flores.
Maria Gertrudis Cantu. In 1735, she requested a dispensation to marry Francisco Miguel Davila, son of Francisco Antonio Davila and Rosa Maria Montemayor.