He was born in Valle de Salinas. His father was Joseph de Villarreal, and his mother was Maria de Oropeza.
In 1731, he requested a dispensation to marry Maria Catarina Hinojosa. They were married in Cerralvo. the bride was 15 years old. Dispensation source: Guerra, et. al., Index to the Marriage Investigations of the Diocese of Guadalajara, p.291.
Jose Andres Villarreal. He married Juana Anastacia Longoria, daughter of Juan Diego Longoria and Clara Maria Chapa. He owned Camargo 35 (tract).
Bernardo Villarreal. He married Guadalupe Vela, daughter of Nicolas Vela and Maria Regina Garcia. He owned Camargo 9 (tract).
Jose Gregorio Villarreal, born 1732. He married Maria Olaya Vela, daughter of Salvador Vela and Maria Agueda Longoria.
Lucas Eduardo Villarreal, born 1734. He married Maria Ana Vela, daughter of Salvador Vela and Maria Agueda Longoria. He owned Camargo 91 (tract), Camargo 10 (tract).
Francisco Venancio Villarreal, born 1736. He married Maria Gertrudis Vela. He owned Camargo 11 (tract).
Maria Josefa Villarreal, born 1740. She married Antonio de la Garza. She married Pedro Longoria, son of Juan Diego Longoria and Clara Maria Chapa.
Quiteria Villarreal, born 1743. She married Javier Salinas, son of Jose Antonio Salinas Camacho and Juana Garcia Guajardo. She owned Camargo 18 (tract).
Juan Antonio Villarreal, born 1744.
He died before 1750. Cause of death: killed by Indians.