Domingo Cristobal de Sosa was the son of Francisco Javier de Sosa and Pascuala de los Reyes.
He married Maria de la Ascencion (I).
Antonio de Jesus de Sosa married Matiana Ramirez.
Maria Bartola de Sosa was born circa 1740. She married Juan de Dios Morin.
Maria de Jesus de Sosa was born circa 1742. She married Clemente Vargas, who owned Camargo 40.
Jose Julian de Sosa was born circa 1743. He married Maria de la Asencion Vargas. He owned Camargo 40.
Maria Gertrudis de Sosa was born circa 1746.
Pedro de Sosa was born circa 1748. He owned Camargo 40.
In 1767, as an antiguo agregado, he was granted Camargo 41 by the King of Spain. Although he was a householder in Camargo in 1750 and therefore technically a primitivo poblador, perhaps classed as antiguo agregado because of casta status and the fact that he was married to an Indian woman.