He was born circa 1761. His father was Francisco Guerra, and his mother was Ana Josefa de la Garza. His father owned Porción 66, Mier. In 1782, he lived in Mier in household number 36. The church census recorded that he was single, español, and 21 years old. His household included 8 people. In 1791, he lived in Mier in household number 30. The church census recorded that he was a widower, español, and 30 years old. His household included 6 people.
He married Maria Guadalupe Barrera, daughter of Santiago Barrera and Maria Salome Garcia on 27 May 1784 in Mier. He was 23 years old, and the bride was 20 years old. Their padrino was Jose Bernardo Peña, and their madrina was Maria Balvina Garcia. Her father owned Porción 2, Mier. His wife died on 18 Feb 1785. She was 21 years old.
Juan Jose Guerra, baptized 7 Feb 1785 in Mier. He married Maria Juana Hinojosa, daughter of Marcelo Hinojosa and Rita Garcia on 12 Aug 1816. He owned El Tule grant, Brooks County.