Her father was Nicolas de Treviño, and her mother was Maria de Renteria.
She married Diego de Villarreal, son of Juan Bautista de Villarreal and Luisa de la Garza.
Maria Nicolasa de Villarreal. On 28 Dec 1730, she requested a dispensation to marry Javier Benavides, son of Juan de Benavides and Clara Maria Guiterrez in Real de Sabinas due to 3rd, 4th, and 4th degree cosanguinity.