Her father was Antonio Cortinas de Acosta, and her mother was Isabel Martinez.
She married Joseph de Villarreal, son of Diego de Villarreal and Maria de la Garza.
Alonso de Villarreal. He married Feliciana de Villarreal, daughter of Francisco de Villarreal and Felipa de Treviño.
Maria de Villarreal. She married Juan Garcia, son of Anastacia Garcia.