His father was Diego de Villarreal, and his mother was Tomasa Flores.
He married Agustina de Treviño.
He married Maria Catalina de la Garza. It was his second marriage.
In 1699, he requested a dispensation to marry Nicolasa de la Garza. It was his third marriage. Dispensation source: Guerra, et. al., Index to the Marriage Investigations of the Diocese of Guadalajara, p.270.