His father was Ambrosio de Cepeda Caballero, and his mother was Juana de la Fuente Martinez.
He married Isabel Camacho, daughter of Pedro Camacho and Mariana Gutierrez (de Olea).
He married Cecilia Ximenez. It was his second marriage.
Antonio de Cepeda. He married Francisca Martinez Guajardo, daughter of Juan Martinez Guajardo and Clara de Aguirre.
Josefa Cepeda. She married Antonio de Archiondo.
Leonarda de Cepeda. She married Nicolas de la Fuente, son of Nicolas de la Fuente and Melchora Flores.