His father was Pedro de los Santos Coy, and his mother was Francisca de Morales.
He married Leonarda Martinez Guajardo, daughter of Lorenzo Martinez Guajardo and Yldefonsa Flores de Valdez.
He requested a dispensation to marry Geronima Galindo. They were married on 12 Nov 1710 in Saltillo. It was his second marriage, and her third marriage. Dispensation source: Guerra, et. al., Index to the Marriage Investigations of the Diocese of Guadalajara, 43-14, p.212.
Ildefonsa de los Santos Coy. She married Francisco de Elizondo, son of Francisco de Elizondo and Beatriz Gonzalez de Paredes.
Luisa de los Santos Coy. She married Antonio de Espronseda.