He married Isabel de Arredondo, daughter of Juan de Arredondo Aguero and Maria Francisca de Sosa.
In 1684, he requested a dispensation to marry Maria de la Garza. They were married on 18 Oct 1684. It was his second marriage, and her second marriage. Dispensation source: Guerra, et. al., Index to the Marriage Investigations of the Diocese of Guadalajara, p.23.
Petronila Garcia. She married Jose Gonzalez, son of Antonio Gonzalez Hidalgo and Juana de Treviño y Maya.
Cristobal Garcia de Quintanilla. He requested a dispensation to marry Maria Josefa Botello de Morales. They were married on 1 Apr 1707 in Monterrey. In 1735, he requested a dispensation to marry Luisa Margarita de la Garza.
Juan Francisco Garcia. He married Ana Garcia de Sepulveda, daughter of Jacinto de Sepulveda and Juana de Arredondo.
Isabel Garcia. She married Antonio Flores.