She was born 15 Mar 1707 in Monterrey. Her father was Marcos de Villarreal, and her mother was Maria Flores.
In 1730, she requested a dispensation to marry Joseph de la Garza. She was 23 years old. It was his second marriage. Dispensation source: Guerra, et. al., Index to the Marriage Investigations of the Diocese of Guadalajara, p.90.