He was born circa 1590. His father was Juan de Caliz, and his mother was Catalina Gomez de Coy.
He married Maria Ines de la Cerda, daughter of Fernando de la Cerda and Isabel de Castro.
He married Beatriz Rojo de las Ruelas, daughter of Santos Rojo and Beatriz de las Ruelas Navarro. It was his second marriage.
Maria de la Cerda y Porcallo. She married Diego Fernandez de Castro, son of Gonzalo Fernandez de Castro and Maria Rodriguez.
Pedro de las Santos Rojo Ruelas. He married Maria del Valle, daughter of Rodrigo Flores de Valdez Carballo and Maria Isabel de Salazar y Treviño.
Bernardo de los Santos Coy. He married Juana Cepeda de la Fuente, daughter of Ambrosio de Cepeda Caballero and Juana de la Fuente Martinez.
Diego de los Santos Coy. He married Maria Farias.
Joseph de los Santos Coy. He married Leonarda Guajardo.
Juan de los Santos Coy. He married Maria Diaz.
Catarina de los Santos Coy. She married Francisco Baez de Treviño, son of Jacinto de Cobarrubias and Ana de Salazar. She married Lorenzo Garcia Gutierrez de Lara, son of Lorenzo Garcia and Leonor Abrego Gutierrez.
Ana Maria de los Santos Coy. She married Diego Fernandez de Castro, son of Gonzalo Fernandez de Castro and Maria Rodriguez.
Pedro de los Santos Coy. He married Fancisca de Morales, daughter of Luis de Morales and Juana de Treviño Salazar.
Juan de Caliz Coy, born 1610. He married Francisca Flores de Valdez, daughter of Rodrigo Flores de Valdez Carballo and Maria Isabel de Salazar y Treviño. He married Clara de Saldivar Garcia.