He was born circa 1749. His father was Santiago Barrera, and his mother was Maria Salome Garcia. His father owned Mier 2 grant.
He married Maria Teresa Salinas, daughter of Jose Salinas Camacho and Maria Bartola Peña. Her mother owned Mier 61 grant.
He married Maria Josefa Garcia, daughter of Jose Antonio Garcia and Maria Francisca Bazan on 21 Nov 1799 in Mier. He was 50 years old, and the bride was 24 years old. It was his second marriage.
In 1782, he lived in San Salvador in household number 78. The church census recorded that he was married, español, and 33 years old. His household included 5 people:
Antonio de Jesus Barrera, married, español, age 33.
Maria Teresa Salinas, married, española, age 26.
Juana Maria Barrera, a young child, española, age 6.
Maria Calistra Barrera, a young child, española, age 4.
Jose Andres Barrera, a young child, español, age 1.