He married Patricia de la Garza in 1799.

Fernando de Leon was born circa 1800. He married Maria Antonia Galvan, Maria de la Luz Escalera.

Maria Candelaria de Leon was born circa 1801. She married Jose Miguel Aldrete.

Silvestre de Leon was born circa 1804. He married Rosalia de la Garza.

Maria Guadalupe de Leon was born circa 1805. She married Desiderio Garcia, Cesario de la Garza.

Jose Felix de Leon was baptized on 30 Nov 1805 in Matamoros. He married Salome Leal.

Jose Agapito de Leon was born circa 1807. He married Maria Antonia C. de la Garza.

Maria de Jesus (Chucha) de Leon was born circa 1811. She married Rafael Manchola.

Refugia de Leon was born circa 1812. She married Jose Maria Jesus Carbajal.

Agustina de Leon was born circa 1814. She married Placido Benavides.

Francisca de Leon was born circa 1818. She married Vicente Dosal.