Her father was Gaspar de Lerma, and her mother was Phelipa Franca.
In 1730, she requested a dispensation to marry Diego de Reyna. Dispensation source: Guerra, et. al., Index to the Marriage Investigations of the Diocese of Guadalajara, p.96.
Jose Antonio Reyna, born 1742. He married Maria Gertrudis Perez, daughter of Diego Perez and Maria Garcia in 1767 in Mier.