He married Beatriz de Elizondo, daughter of Pedro de Elizondo and Maria de la Garza.
In 1735, he requested a dispensation to marry Juana de Escamilla. It was his second marriage. Dispensation source: Guerra, et. al., Index to the Marriage Investigations of the Diocese of Guadalajara, p.94.
In 1714, he requested a dispensation to marry Margarita Gonzalez. It was his third marriage. Dispensation source: Guerra, et. al., Index to the Marriage Investigations of the Diocese of Guadalajara, p.56.
Joseph Cayetano de la Garza. In 1746, he requested a dispensation to marry Ana Josefa de la Garza.
Juana Maria de la Garza. In 1748, she requested a dispensation to marry Joseph Cristobal de la Garza.
Joseph Joaquin de la Garza. In 1747, he requested a dispensation to marry Josepha Gertrudis Cantu.