Her father was Bernabe de Villarreal, and her mother was Maria Isabel de la Garza.
She married Nicolas Gutierrez de Lara, son of Nicolas Gutierrez de Lara and Clara de Treviño Renteria.
Isabel Gutierrez de Lara. In 1715, she requested a dispensation to marry Ildefonso (Alonso) de la Garza. She married Antonio Garcia de Sepulveda, son of Jacinto Garcia de Sepulveda and Clara de Renteria.