His father was Pedro Flores, and his mother was Melchora Gutierrez de Abrego.
He married Ana Maria de la Cerda.
Isabel Flores de Abrego. She married Juan Ramos de Arriola. She married Antonio Morales, son of Luis de Morales and Juana de Treviño Salazar.
Francisca Flores de Abrego. She married Rodrigo Flores de Valdez, son of Juan Flores de Valdez and Francisca de Cepeda de la Fuente.
Pedro Flores de Abrego. He married Polonia de Treviño.