He was born circa 1779. His father was Jose Miguel Escamilla, and his mother was Juliana Moya.
He married Ana Dominga Nepomucena Moreno, daughter of Nepomuceno Moreno and Dorotea Serna on 27 Nov 1799 in Guajuco. He was 20 years old, and the bride was 17 years old. Their padrino was Antonio Cerna, and their madrina was Maria Josefa Escamilla.
Juan Jose Escamilla, baptized 18 May 1804 in Guajuco (Santiago). His padrino was Pedro Garcia, and his madrina was Maria Francisca Garcia. He married Maria Francisca Martinez, daughter of Jose Maria Bravo and Maria del Carmen Garza on 26 May 1824 in Guajuco.