He was born circa 1763. His father was Santiago Barrera, and his mother was Maria Salome Garcia. His father owned Porción 2, Mier. In 1782, he lived in Mier in household number 1. The church census recorded that he was single, español, and 19 years old. His household included 10 people. In 1791, he lived in Mier in household number 3. The church census recorded that he was single, español, and 28 years old. His household included 9 people.
He married Maria Josefa Ramirez Vela, daughter of Jose Antonio Ramirez and Catarina Vela in 1800. He was 37 years old, and the bride was 27 years old. It was her second marriage. Her father owned Porción 67, Mier, Starr County.
Maria Yrinea Barrera. She married Francisco Barrera, son of Manuel Barrera and Maria Antonia Saenz on 22 Jan 1830 in Mier.