He married Maria Guadalupe Garcia.
Jose Gregorio Barrera was born circa 1749. He married Maria Juliana Benavides. He owned Mier 38.
Maria Guadalupe Barrera was born circa 1752. She married Jose Tomas Gonzalez.
Maria Rita Barrera was born circa 1752. She married Tomas de la Garza.
In 1767 he was granted Mier 38 by the King of Spain.