She was born circa 1756. Her father was Francisco de la Garza, and her mother was Juana Josefa de Lerma.
She married Cristobal de la Rosa, son of Manuel de la Rosa and Teresa Treviño on 1 Feb 1773 in Mier. She was 17 years old, a native of Monterrey, and the groom was 22 years old, a native of Camargo.
In 1782, she lived in Junta de los Rios in household number 111. The church census recorded that she was married, casta, and 26 years old. Her household included 4 people:
Cristobal de la Rosa, married, casta, age 31.
Leonor Garza, married, casta, age 26.
Maria Gertrudis de la Rosa, a child, casta, age 7.
Ana Gertrudis de la Rosa, a young child, casta, age 3.