He was born circa 1747. His father was Francisco de la Garza, and his mother was Maria Candida Garcia Sepulveda. His father owned Camargo 65 grant.
He married Maria Rita Barrera, daughter of Tomas Barrera and Maria Guadalupe Garcia on 1 Dec 1772 in Mier. He was 25 years old, and the bride was 20 years old. Her father owned Mier 38 grant.