He married Leonor (Isabel) Gutierrez.

Leonor Abrego Gutierrez married Lorenzo Garcia.

Maria de Abrego married Domingo Gonzalez (Navarro?).

Isabel Gutierrez married Juan Martinez de Salazar, Juan de Morales Gomez.

Agustin de Abrego.

Bernardina Abrego Gutierrez married Francisco de Treviño.

Melchora de Abrego was baptized on 25 Jan 1587 in Nuestra Señora de las Nieves, Nueva Galicia. She married Pedro Flores.

Juan de Abrego y Gutierrez was baptized on 22 Jul 1590 in Nieves, Nueva Galicia.

Rodrigo de Abrego y Gutierrez was baptized on 26 Jan 1592 in Nieves, Nueva Galicia.